I am a Postdoctoral Training Fellow in the Genomics and Evolutionary Dynamics lab at the Institute of Cancer Research (ICR). I joined the ICR in November 2023 after completing my DPhil in Mathematical Biology, entitled "Investigating the impact of growth arrest mechanisms on tumour growth and responses to combinations of radiotherapy and hyperthermia", at the University of Oxford under the supervision of Prof. Helen Byrne and Prof. Philip Maini.

My research lies at the interface of mathematics, data science and cancer biology. I develop mechanistic mathematical models of cancer evolution, from tumour initiation and growth to treatment response and disease progression, alongside mathematical and statistical methods for analysing multimodal molecular data.

My work aims to uncover the biological mechanisms that shape cancer evolution, with a particular interest in the interplay between clonal evolution, phenotypic plasticity and the tumour microenvironment. During my doctoral research, I developed and analysed mechanistic models of tumour growth, invasion and response to combinations of radiotherapy and hyperthermia. My current research takes a data-driven, population-genetic approach to investigating phenotypic plasticity during metastatic progression, integrating mathematical modelling with single-cell multimodal genomic and epigenomic data.

Website updated September 2026.

contact me at chloe [dot] colson [at] my institution

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